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Since I joined the Hackintosh scene I've always loved to run macOS on AMD hardware because of my "think REALLY different" way of living the Apple world: using an officially not supported cpu on a non official hardware doubles the fun to make macOS work fine with standard PCs. Thanks to the AMD vanilla patches we can run even the latest macOS on modern AMD machines without creating a custom kernel, but there are still some caveats. Certain apps use the infamous Intel MKL libraries, now called Intel OneAPI: those libraries are x86_64 compliant but in the macOS porting certain functions work only on genuine intel cpus: these are __intel_fast_memset.A and __intel_fast_memcpy.A. We can fool these libraries redirecting those calls to __intel_fast_memset.J and __intel_fast_memcpy.J which work perfectly on AMD Hackintoshes, and as fast as possible given the fact that we lack AVX512. But we also need to fool them changing the function __mkl_serv_intel_cpu_true returning TRUE even when running on AMD cpus. Using only these three "patches" we can make every intel only app run on our AMD Hacks natively without using hypervisors and without bypassing or deleting important functions / files of our specific app. It is possible to have SIP Enabled or Disabled. Some examples below: After Effects CC Libraries to be patched: 1) libiomp5.dylib 2) libmkl_core.1.dylib 3) libmkl_avx512.1.dylib Photoshop: Library / plugin to be patched: 1) libmkl_core.dylib 2) Adaptive Wide angle Premiere Pro: Effects / plugins to be patched: 1) Stabiliser 2) Rolling Shutter 3) Morph Cut If you want to keep SIP enabled we need to force codesigning of our modified binaries. You can achieve this by running in terminal, for each modded binary: sudo codesign --force --deep --sign - as an example if we patch the Premiere Pro "MorphCut" plugin we must issue this command to recreate the correct sign for this binary: sudo codesign --force --deep --sign - /Applications/Adobe\ Premiere\ Pro\ 2021/Adobe\ Premiere\ Pro\ 2021.app/Contents/Plug-Ins/Common/AEFilterMorphCut.bundle given that we have modified the macOS executable inside this path: /Applications/Adobe Premiere Pro 2021/Adobe Premiere Pro 2021.app/Contents/Plug-Ins/Common/AEFilterMorphCut.bundle/Contents/MacOS Adobe Photoshop 22.5.1 Adobe After Effects 18.4.1 Adobe Premiere Pro 15.4.1 Autodesk Autocad 2022 Autodesk Maya 2022 Wolfram Mathematica 12.3 Matlab 2021a MatLab 2021b Skylum Luminar AI 2021 Topaz Gigapixel AI Discord Krisp AI 1.30.10 + 1.31.22 Waves 13 Complete Neo 0.9.1 Luminar Adobe After Effects 22.1.2 Adobe Premiere Pro 22.1.2 Adobe Photoshop 23.1 Adobe Photoshop 23.2.0 After Effects 22.3.0 (Build 47) PyTorch 1.10.2 Krisp 1.32 and up